Basic Information
VIS ID
TVIS10000471
Fusion event
HBV-chr9 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
q13
Reference genome
GRCh37/hg19
Start
66971304/63066332 (Hg38)
End
66971304/63066332 (Hg38)
Fragile sites / regions
FRA9F
Nearest miRNA
hsa-mir-101-2/Upstream/21832497; hsa-let-7a-1/Downstream/7743643;
Nearest TSS
ENST00000422679/Upstream/168226; ENST00000431077/Downstream/662545;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/150287, chr9-CpG: 299/Downstream/382538
Nearby gene
PTGER4P2-CDK2AP2P2(-468274) ; PRPF31(+46071) ;
Upstream sequence
TTTCCAACGAAATCCTCAAAGCTATCCAAATATCCACTTGCAGATTCTACAAAAAGAGTGTTTCAAAACTGCTCT
Junction sequence
TTTCCAACGAAATCCTCAAAGCTATCCAAATATCCACTTGCAGATTCTACAAAAAGAGTGTTTCAAAACTGCTCTGTCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate