Basic Information
VIS ID
TVIS10000478
Fusion event
HBV-chr10 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
85852821/84093065 (Hg38)
End
85852821/84093065 (Hg38)
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-1265/Upstream/8540512; hsa-mir-107/Downstream/2171629;
Nearest TSS
ENST00000439456/Upstream/180143; ENST00000372134/Downstream/46375;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/527819, chr10-CpG: 51/Downstream/46237
Nearby gene
NRG3(-1105995) ; GHITM(+46255) ;
Downstream sequence
CTGTCCTGAAGGCAGTAAAATTACTTTATGGATACATATTTGTTGGGGGAACTTAAAGATAGATAAATGAAAGAAAGAGAGATAAACAGGGATTAGCCTAC
Junction sequence
GAATTGTGGGTCTTTTGGGCTTTGCTGCCCCTTTTACACAATGTGGTTCTGTCCTGAAGGCAGTAAAATTACTTTATGGATACATATTTGTTGGGGGAACTTAAAGATAGATAAATGAAAGAAAGAGAGATAAACAGGGATTAGCCTAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate