Basic Information
VIS ID
TVIS10000484
Fusion event
HBV-LOC100996643 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
q13
Reference genome
GRCh37/hg19
Start
67348126/63393154 (Hg38)
End
67348126/63393154 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA9F
Target gene
LOC100996643
Nearest miRNA
hsa-mir-101-2/Upstream/22159319; hsa-let-7a-1/Downstream/7416821;
Nearest TSS
ENST00000422679/Upstream/495048; ENST00000431077/Downstream/335723;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/477109, chr9-CpG: 299/Downstream/55716
Nearby gene
AQP7P1(-58634) ; FAM27E3(+436818) ;
Downstream sequence
TGGGTCATGGCAGTGCCTGGTCAACTCCGGGGCAGGGCCAGAAGCAGGACAGGGACAGGGCCAATGCTCAGGCCAGGGACAGGGCATGACAGGACGTGCCAG
Junction sequence
GAATCCAGATTCATCAACTCACCCCAACACAGAATAGCTTGCCTGAGTGCTGGGTCATGGCAGTGCCTGGTCAACTCCGGGGCAGGGCCAGAAGCAGGACAGGGACAGGGCCAATGCTCAGGCCAGGGACAGGGCATGACAGGACGTGCCAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate