Basic Information
VIS ID
TVIS10000487
Fusion event
HBV-chr20 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr20
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
16062493/16081848 (Hg38)
End
16062493/16081848 (Hg38)
Nearest miRNA
hsa-mir-103a-2/Upstream/5432153; hsa-mir-1-1/Downstream/2388767;
Nearest TSS
ENST00000382410/Upstream/96060; ENST00000616572/Downstream/288788;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/2085426, chr20-CpG: 50/Downstream/491343
Nearby gene
MACROD2(-28652) ; KIF16B(+190256) ;
Downstream sequence
ACCCTGCTTGGAAGCCAATAGCCA
Junction sequence
GGTAGGAAGAGTTTGCCATTAGGATTAAGCAAGGTACCGTAGAAGAATAAAGCCCCGTAAAGTTTCCCACCTTATGTGTCCAAGGAATACTAACCCTGCTTGGAAGCCAATAGCCA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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