Basic Information
VIS ID
TVIS10000492
Fusion event
HBV-LOC105374188 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
163053339/163335551 (Hg38)
End
163053339/163335551 (Hg38)
Location type
Intronic
Target gene
LOC105374188
Nearest miRNA
hsa-let-7g/Upstream/2930726; hsa-mir-1224/Downstream/835920;
Nearest TSS
ENST00000440867/Upstream/32229; ENST00000477099/Downstream/26012;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1962690, chr3-CpG: 20/Downstream/668711
Nearby gene
LINC01192(-32250) ; SI(+1643347) ;
Downstream sequence
TCACAACACCAGTAGGCAGTACCCAATGAGGACTCTGTGTAGAGGCTCCAGCTTCAGAATTCCCTACCACAATGCTCTAGCAGAGGTTCTGCATGAGGGCCCCATCCCTGAAGCAAACTTCAA
Junction sequence
CCGGTAGGAGCTGCTTAGATTGTATACATGCATATAAAGGCATTAAGGCAGGATAGCCACATTCACAACACCAGTAGGCAGTACCCAATGAGGACTCTGTGTAGAGGCTCCAGCTTCAGAATTCCCTACCACAATGCTCTAGCAGAGGTTCTGCATGAGGGCCCCATCCCTGAAGCAAACTTCAA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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