Basic Information
VIS ID
TVIS10000499
Fusion event
HBV-chr17 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr17
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
22247938/22748611 (Hg38)
End
22247938/22748611 (Hg38)
Nearest miRNA
hsa-mir-1180/Upstream/3404037; hsa-mir-10226/Downstream/4545299;
Nearest TSS
ENST00000595228/Upstream/55777; ENST00000583786/Downstream/4251314;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/55929, chr17-CpG: 114/Downstream/3982417
Nearby gene
MTRNR2L1(-223947) ;
Downstream sequence
TAAACTTCTTTGTGATGTTTGCTTTCAACTCACAGAGTTGAACTTTCCTTTTGAGAGAGAAGCTTTGAAACACTCTTTTTCTAGAATCTGCAAGTGGATATTTGGAGGGCTTTGAGGCCTGTGGTGGAAAAGGAATTATCTTCCCGTAAGAACTAGATAGATGC
Junction sequence
CCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGCGACTCTACCGTCCCCTTCTTCATCTGCCGTAAACTTCTTTGTGATGTTTGCTTTCAACTCACAGAGTTGAACTTTCCTTTTGAGAGAGAAGCTTTGAAACACTCTTTTTCTAGAATCTGCAAGTGGATATTTGGAGGGCTTTGAGGCCTGTGGTGGAAAAGGAATTATCTTCCCGTAAGAACTAGATAGATGC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate