Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000501
Fusion event
HBV-STK10 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q35.1
Reference genome
End
171567872/172140868 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-1225-3p ; hsa-mir-1233-3p ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-214-3p ; hsa-mir-302c-3p ; hsa-mir-3617-3p ; hsa-mir-3619-5p ; hsa-mir-365a-5p ; hsa-mir-365b-5p ; hsa-mir-3940-3p ; hsa-mir-4291 ; hsa-mir-4519 ; hsa-mir-4652-5p ; hsa-mir-520f-3p ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-6849-3p ; hsa-mir-761 ; hsa-mir-922
Nearest miRNA
hsa-mir-10397/Upstream/754108; hsa-mir-10523/Downstream/521297;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/85095, chr5-CpG: 162/Downstream/46558
Nearest cancer related gene
STK10(TSG, No orient, 0)
Downstream sequence
ATGTCCACCAAGAGATGAATGGATAAAGAAAATGTAGTATGTACACACAATGGATCCCTATTCTA
Junction sequence
GGAAACCACCGTGAACGCCCACAGGAACCTGCCCAAGGTCTTGCATAAGAGGACTCTTGGACTTTAGGTCTTGCATAAGAGGACTCTTGGACTTTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTGTTTAATGAGTGGGAGGAGTTGGGGGATTGTACTAGGAGGCTGTAGGCATAAATTGGTGCGTTCATGTCCACCAAGAGATGAATGGATAAAGAAAATGTAGTATGTACACACAATGGATCCCTATTCTA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.