DTD1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000505
Fusion event
HBV-DTD1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
18708080/18727436 (Hg38)
End
18708080/18727436 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA20A
Target gene
DTD1
miRNAs that regulate target gene
hsa-mir-145-5p ; hsa-mir-16-5p ; hsa-mir-142-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/256745; hsa-mir-1-1/Downstream/7480750;
Nearest TSS
ENST00000382410/Upstream/28727; ENST00000609087/Downstream/66557;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/138988, chr20-CpG: 155/Downstream/484379
Upstream sequence
AGATCCCTTCCAGGGCCGCCCTCTCCTTCAGGGCCGAAGAGCATCA
Junction sequence
AGATCCCTTCCAGGGCCGCCCTCTCCTTCAGGGCCGAAGAGCATCATCAAGGTGTTACAGAAGTCCACCCAGACCCAGCTTCAAAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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