Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000511
Fusion event
HBV-PXDNL integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q11.22
Reference genome
Start
End
52296331/51383771 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-124-1/Upstream/8487496; hsa-mir-10400/Downstream/10331017;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1473471, chr8-CpG: 98/Downstream/24831
Downstream sequence
ATGAACTATTTCTTGCCACAGAGACCACAGTGTCAAGCCATATCTAATTTCATAATGACAGTTTCACTTAAAGTTGGC
Junction sequence
TGGAAGACCCAGCATCCAGGGAATTAGGAGTCGGCTATGTCAATGTTAATATGGGCCTAAAACTCAGACAACTACTGTGGTTAATGAACTATTTCTTGCCACAGAGACCACAGTGTCAAGCCATATCTAATTTCATAATGACAGTTTCACTTAAAGTTGGC
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.