hsa-mir-1294 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000520
Fusion event
HBV-KMT2B integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
36213567/35722665 (Hg38)
End
36213567/35722665 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
KMT2B
miRNAs that regulate target gene
hsa-mir-7515 ; hsa-mir-302a-5p ; hsa-mir-3154 ; hsa-mir-6782-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-5692a ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-20b-5p ; hsa-mir-153-3p ; hsa-mir-1224-3p ; hsa-mir-1294 ; hsa-mir-1914-3p ; hsa-mir-214-3p ; hsa-mir-31-5p ; hsa-mir-3184-5p ; hsa-mir-3619-5p ; hsa-mir-3689d ; hsa-mir-423-5p ; hsa-mir-4316 ; hsa-mir-4426 ; hsa-mir-4440 ; hsa-mir-4459 ; hsa-mir-4647 ; hsa-mir-4662b ; hsa-mir-4688 ; hsa-mir-4722-5p ; hsa-mir-5194 ; hsa-mir-6085 ; hsa-mir-6165 ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6743-5p ; hsa-mir-6789-5p ; hsa-mir-6813-5p ; hsa-mir-6851-5p ; hsa-mir-761 ; hsa-mir-7704 ; hsa-mir-885-3p
Nearest miRNA
hsa-mir-10395/Upstream/377038; hsa-let-7e/Downstream/3686958;
Nearest TSS
ENST00000633603/Upstream/1763; ENST00000592092/Downstream/10593;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/2641, chr19-CpG: 24/Downstream/1061
Downstream sequence
CATCTTCAGGCACCATGGCCCGGGCCTGACCCAGGGCCACAGCAGCATGACGGCAGACATGTTTGATGCGGGGACCTTGCACAGGGGACTCGGGACCCTGGGGGAGAAATCGGAGGTGTGTGGGCT
Junction sequence
CAACGTCGCATGGTATGATGTATACTTGCGGGAGAGCACGACAGAATTGTCAGTCCCGATGAGTTTTGCCCCAGACCTGCTGCGAGCACCATCTTCAGGCACCATGGCCCGGGCCTGACCCAGGGCCACAGCAGCATGACGGCAGACATGTTTGATGCGGGGACCTTGCACAGGGGACTCGGGACCCTGGGGGAGAAATCGGAGGTGTGTGGGCT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate