hsa-mir-892b _LIHC.png
CCNE1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000523
Fusion event
HBV-CCNE1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
q12
Reference genome
GRCh37/hg19
Start
30293497/29802590 (Hg38)
End
30293497/29802590 (Hg38)
Location type
Intronic
Target gene
CCNE1
miRNAs that regulate target gene
hsa-mir-15b-5p ; hsa-mir-503-5p ; hsa-mir-424-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-107 ; hsa-mir-185-5p ; hsa-mir-103a-3p ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-16-1-3p ; hsa-mir-195-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-151a-3p ; hsa-mir-342-5p ; hsa-mir-125b-5p ; hsa-mir-92a-3p ; hsa-mir-383-3p ; hsa-mir-497-5p ; hsa-mir-4524a-5p ; hsa-mir-4694-3p ; hsa-mir-4524b-5p ; hsa-mir-6838-5p ; hsa-mir-7-5p ; hsa-mir-4477a ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-5191 ; hsa-mir-646 ; hsa-mir-25-5p ; hsa-mir-30c-2-3p ; hsa-mir-144-5p ; hsa-mir-892b
Nearest miRNA
hsa-mir-10395/Upstream/9403236; hsa-let-7e/Downstream/5320110;
Nearest TSS
ENST00000633603/Upstream/86801; ENST00000586912/Downstream/9308;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/77903, chr19-CpG: 137/Downstream/8798
Nearest cancer related gene
CCNE1(OG, No orient, 0)
Upstream sequence
AAGAAACTCCATCAGTTGTCCCCAAACACAGGA
Junction sequence
AAGAAACTCCATCAGTTGTCCCCAAACACAGGACACTCTGGGGCATCTAGCAGAGCTTGGTGGAATGTTGTGGAGTTCCACTGCATGGCCTGAGGATGACTGTCTCTTAGAGGTGGAGAGATGGGAGTAGGCTGTCTTCCTGACTGCCGAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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