Basic Information
VIS ID
TVIS10000526
Fusion event
HBV-chr16 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
73981492/73947593 (Hg38)
End
73981492/73947593 (Hg38)
Nearest miRNA
hsa-mir-1225/Upstream/3917171; hsa-mir-11401/Downstream/2921343;
Nearest TSS
ENST00000527434/Upstream/55722; ENST00000561669/Downstream/47122;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/880701, chr16-CpG: 74/Downstream/349042
Nearby gene
PRPF31(-526197) ;
Downstream sequence
AGGCAGGAGAATTGCTTTAACCTGGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCGCTGTTGCACTCCAGCCTGGGCAACAAGAGCGAAATCCAGTC
Junction sequence
AAGAGTCCTCTTATGTAAGACCTTGGGCAAGACCTGGTGGGCGTTCACGGTGGTCTCCATGCGACGTGCAGAGGCAGGAGAATTGCTTTAACCTGGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCGCTGTTGCACTCCAGCCTGGGCAACAAGAGCGAAATCCAGTC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate