Basic Information
VIS ID
TVIS10000540
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
121485255/121743457 (Hg38)
End
121485255/121743457 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/4648729; hsa-mir-1182/Downstream/24107130;
Nearest TSS
ENST00000473358/Upstream/162933; ENST00000443018/Downstream/21757055;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/223730, chr1-CpG: 312/Downstream/3342052
Nearby gene
EMBP1(-171569) ;
Upstream sequence
AACTCACAGAGTTGAACGATCCTTTACACAGAGCAGACTTGAAACACTCTTTTTGTGGAATTTGCAAGTGGAGATTTCAGCCGCTTTGAGGTCAATGGTAGAATAGGAAATATCTTCGTAGAAAAACTAGACAGAAT
Junction sequence
AACTCACAGAGTTGAACGATCCTTTACACAGAGCAGACTTGAAACACTCTTTTTGTGGAATTTGCAAGTGGAGATTTCAGCCGCTTTGAGGTCAATGGTAGAATAGGAAATATCTTCGTAGAAAAACTAGACAGAATTATTTATGCCTACAGCCTCCTAGTACAAAGATCATTAACCTAA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate