Basic Information
VIS ID
TVIS10000547
Fusion event
HBV-chr7 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
61974921/62514543 (Hg38)
End
61974921/62514543 (Hg38)
Fragile sites / regions
FRA7J
Nearest miRNA
hsa-mir-1183/Upstream/5109453; hsa-mir-10399/Downstream/1106547;
Nearest TSS
ENST00000635602/Upstream/5064366; ENST00000418297/Downstream/539888;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/133646, chr7-CpG: 49/Downstream/539594
Nearby gene
ZNF733P(+776749) ;
Upstream sequence
GAGCAGATTCGAAACACTCTTTTTCTGCAATTTGCAAGTGGAGACTTCA
Junction sequence
GAGCAGATTCGAAACACTCTTTTTCTGCAATTTGCAAGTGGAGACTTCAAGCGCTTTGAGGCCAAAGGCGGAGTAGCCCCAACGTTNTGGTTTTATTAGGGTTCAAATGTATACCCAAAGACAAAAGAAAATTGGTAACAGCGGTAAAAAGGGACTCAAGATGT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate