Basic Information
VIS ID
TVIS10000548
Fusion event
HBV-chr13 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr13
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
62198455/61624322 (Hg38)
End
62198455/61624322 (Hg38)
Fragile sites / regions
FRA13B
Nearest miRNA
hsa-mir-1297/Upstream/424442; hsa-mir-1267/Downstream/4342008;
Nearest TSS
ENST00000623511/Upstream/196376; ENST00000455977/Downstream/405226;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1226411, chr13-CpG: 36/Downstream/2187264
Nearby gene
PCDH20(-208800) ;
Upstream sequence
ACAAAGGACAGCTGGAGGCATCACGCTACCTGACTTCAAATTATACTACAAGGCCACAATAACCAAACCAGCATGGTACTGGTACCAAAACAGATATAGATATAGATATACATATA
Junction sequence
ACAAAGGACAGCTGGAGGCATCACGCTACCTGACTTCAAATTATACTACAAGGCCACAATAACCAAACCAGCATGGTACTGGTACCAAAACAGATATAGATATAGATATACATATAGACCTTGGGCAAGACCTGGTGGGCGTTCACGGTGGTCTCCATGCGACGTGCAGAGGTGAAGCGAAGTGCACACGGTCCGGCAGATGAGAAGGCACAGACGGGGAGACCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGCCGGAACGGCAGACGAAGAAGGGGACGGTAGAGTCCCAAACGGCCCCGAGACGGGTCGTCCGCGGGATTCAGCGCCGACGGGACGTAGACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACACCCTAGCAGCCATGGAAAGGGAGGTGTA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate