Basic Information
VIS ID
TVIS10000564
Fusion event
HBV-chr8 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q24.22
Reference genome
GRCh37/hg19
Start
132492876/131480629 (Hg38)
End
132492876/131480629 (Hg38)
Nearest miRNA
hsa-mir-1204/Upstream/1472176; hsa-mir-10400/Downstream/1565852;
Nearest TSS
ENST00000518652/Upstream/170157; ENST00000520362/Downstream/423459;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/438126, chr8-CpG: 92/Downstream/423374
Nearby gene
ADCY8(-440041) ; EFR3A(+423480) ;
Upstream sequence
CATGAAACTTATTCGCTATCACGAGAACAGCATGTGAAAACCTCCCCTATTATTCAGTTAGCTCCCACTGGTCCCTCCCACAACATATGGGGATTATGGGAG
Junction sequence
CATGAAACTTATTCGCTATCACGAGAACAGCATGTGAAAACCTCCCCTATTATTCAGTTAGCTCCCACTGGTCCCTCCCACAACATATGGGGATTATGGGAGGTAGAGTCCCAAACGGCCCCGAGACGGGTCGTCCGCGGGATTCAGCGCCGACGGGACGTAGACAAAGGA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate