VISDB Viral Integration Site DataBase

VIS ID

TVIS10000567

Fusion event

HBV-TP53 integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

7578702/7675384 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-25-3p ; hsa-mir-30d-5p ; hsa-mir-1285-3p ; hsa-mir-612 ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-221-3p ; hsa-mir-222-3p ; hsa-mir-214-3p ; hsa-mir-10b-5p ; hsa-mir-34a-5p ; hsa-mir-608 ; hsa-mir-605-5p ; hsa-mir-504-5p ; hsa-mir-485-5p ; hsa-mir-27a-3p ; hsa-mir-454-3p ; hsa-mir-324-5p ; hsa-mir-150-5p ; hsa-mir-375 ; hsa-mir-200a-3p ; hsa-mir-491-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30e-5p ; hsa-mir-19b-3p ; hsa-mir-92a-2-5p ; hsa-mir-92a-1-5p ; hsa-mir-20a-5p ; hsa-mir-18a-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-17-5p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7150 ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-7110-5p ; hsa-mir-4651 ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-6825-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6731-5p ; hsa-mir-8085 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-1273f ; hsa-mir-6760-5p ; hsa-mir-5197-5p ; hsa-mir-2110 ; hsa-mir-4531 ; hsa-mir-937-5p ; hsa-mir-223-3p ; hsa-mir-4697-3p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-5702 ; hsa-mir-4795-5p ; hsa-mir-4682 ; hsa-mir-194-3p ; hsa-mir-5693 ; hsa-mir-622 ; hsa-mir-4650-5p ; hsa-mir-1972 ; hsa-mir-1296-3p ; hsa-mir-513b-3p ; hsa-mir-6749-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-4286 ; hsa-mir-5196-3p ; hsa-mir-5003-5p ; hsa-mir-3065-5p ; hsa-mir-3529-3p ; hsa-mir-3165 ; hsa-mir-6880-5p ; hsa-mir-8071 ; hsa-mir-6882-5p ; hsa-mir-1264 ; hsa-mir-19a-3p ; hsa-mir-377-3p ; hsa-mir-300 ; hsa-mir-663a ; hsa-mir-1228-3p ; hsa-mir-151a-5p ; hsa-mir-26a-1-3p ; hsa-mir-28-5p ; hsa-mir-125b-1-3p ; hsa-mir-518c-3p ; hsa-mir-638 ; hsa-mir-28-3p ; hsa-mir-24-3p ; hsa-mir-155-3p ; hsa-mir-150-3p ; hsa-mir-214-5p ; hsa-mir-1225-3p ; hsa-mir-1247-3p ; hsa-mir-330-3p ; hsa-mir-4276 ; hsa-mir-505-5p ; hsa-mir-5587-3p

Nearest miRNA

hsa-mir-1253/Upstream/452005; hsa-mir-10226/Downstream/412672;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/23364, chr17-CpG: 23/Downstream/10588

Nearest cancer related gene

TP53(TSG, No orient, 0)

Downstream sequence

TGAGGTGTCGACGCCAACTCTCTCTAGCTCGCTAGTGGGTT

Junction sequence