Basic Information
VIS ID
TVIS10000569
Fusion event
HBV-SUGCT integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
40788892/40749293 (Hg38)
End
40788892/40749293 (Hg38)
Location type
Intronic
Target gene
SUGCT
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1183/Upstream/3829861; hsa-mir-10399/Downstream/2401602;
Nearest TSS
ENST00000635602/Upstream/202365; ENST00000460466/Downstream/43889;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/613874, chr7-CpG: 26/Downstream/956287
Upstream sequence
GTCCGTGAATCCTCTAGTCTTTTTTGGCTTCATTTGGTGTATTATAGGATGAAACGTTATTTTATGTCAAATGTTTA
Junction sequence
GTCCGTGAATCCTCTAGTCTTTTTTGGCTTCATTTGGTGTATTATAGGATGAAACGTTATTTTATGTCAAATGTTTATGTAAGACCTTGGGCAAGACCTGGTGGGCGTTCACGGTGGTCTCCATGCGACGTGCAGAGGTGAAGCGAAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate