VISDB Viral Integration Site DataBase

VIS ID

TVIS10000570

Fusion event

HBV-RNF44 integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr5

Cytoband

q35.2

Reference genome

Start

End

175957501/176530500 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-9-5p ; hsa-mir-221-3p ; hsa-mir-101-3p ; hsa-mir-98-5p ; hsa-mir-93-5p ; hsa-mir-296-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-4708-3p ; hsa-mir-202-3p ; hsa-mir-6830-5p ; hsa-mir-3607-3p ; hsa-mir-4802-3p ; hsa-mir-942-3p ; hsa-mir-3662 ; hsa-mir-1252-3p ; hsa-let-7a-5p ; hsa-let-7d-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-let-7e-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-338-5p ; hsa-mir-580-5p ; hsa-mir-5692a ; hsa-mir-92b-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-3918 ; hsa-mir-7160-3p ; hsa-mir-5580-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-3671 ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-513c-5p ; hsa-mir-514b-5p ; hsa-mir-616-5p

Nearest miRNA

hsa-mir-10397/Upstream/162469; hsa-mir-1229/Downstream/98939;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/82073, chr5-CpG: 135/Downstream/5997

Downstream sequence

AGGCAGGCCCACCGGGCTGACTTGCACGTGGGCT

Junction sequence