Basic Information
VIS ID
TVIS10000572
Fusion event
HBV-CENPC integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
68386890/67521172 (Hg38)
End
68386890/67521172 (Hg38)
Location type
Intronic
Target gene
CENPC
Nearest miRNA
hsa-mir-12113/Upstream/1244244; hsa-mir-1243/Downstream/9052396;
Nearest TSS
ENST00000502981/Upstream/6927; ENST00000265404/Downstream/9694;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1850216, chr4-CpG: 37/Downstream/24103
Downstream sequence
GTTTCCCTGATTGTATTCCTGAGATTTGGTTACTTATGTTAGGG
Junction sequence
TGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTGATTGTATTCCTGAGATTTGGTTACTTATGTTAGGG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate