Basic Information
VIS ID
TVIS10000574
Fusion event
HBV-chr8 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
63064041/62151482 (Hg38)
End
63064041/62151482 (Hg38)
Nearest miRNA
hsa-mir-124-1/Upstream/436623; hsa-mir-10400/Downstream/2227667;
Nearest TSS
ENST00000518652/Upstream/261643; ENST00000524201/Downstream/97109;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/6629, chr8-CpG: 120/Downstream/96557
Nearby gene
MIR4470(-436623) ; FLJ39630(+97460) ;
Downstream sequence
AGGGTCCCCTTTTCTTCAGTTGTTGTAACAATGTTCTCTTCGTTGTCTTTCAAG
Junction sequence
GGAAGACAGCCTACTCCCCTCTCTCCACCTCTAAGAGACAGTCATCCTCAGGCCATGCAATGGAACTCCCGCACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATAGGGTCCCCTTTTCTTCAGTTGTTGTAACAATGTTCTCTTCGTTGTCTTTCAAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate