Basic Information
VIS ID
TVIS10000579
Fusion event
HBV-chr2 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
195176679/194311955 (Hg38)
End
195176679/194311955 (Hg38)
Nearest miRNA
hsa-mir-10b/Upstream/5178844; hsa-mir-1244-1/Downstream/12471279;
Nearest TSS
ENST00000437798/Upstream/413588; ENST00000438505/Downstream/32314;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2115869, chr2-CpG: 150/Downstream/1344876
Nearby gene
PCGEM1(-1535054) ; SLC39A10(+1344853) ;
Downstream sequence
ACCTTCCTAGTAGTATTGAAGATAAAACATATTACAGTGGTAATTTCCAGATAATTTACTTTGCTGAGATTCAAGATAAAAATAAACTCTACCTTATTAGCTCCATCCTAGCAGCAGA
Junction sequence
GGCAGTAGCTTGGAGGCTTGACAGTAGGACATGAACATGAGATGATTAGGCAGAGGACCTTCCTAGTAGTATTGAAGATAAAACATATTACAGTGGTAATTTCCAGATAATTTACTTTGCTGAGATTCAAGATAAAAATAAACTCTACCTTATTAGCTCCATCCTAGCAGCAGA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate