Basic Information
VIS ID
TVIS10000588
Fusion event
HBV-chr8 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
53704683/52792123 (Hg38)
End
53704683/52792123 (Hg38)
Nearest miRNA
hsa-mir-124-1/Upstream/9895848; hsa-mir-10400/Downstream/8922665;
Nearest TSS
ENST00000518652/Upstream/46280; ENST00000331251/Downstream/146308;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/77182, chr8-CpG: 235/Downstream/147018
Nearby gene
RB1CC1(-77657) ; NPBWR1(+147785) ;
Nearest cancer related gene
RB1CC1(TSG, -77657) ;
Downstream sequence
GCTCTTTCCTCTCTTTTCTGCCATCACAGTACAGTTGGATGT
Junction sequence
GAGGGACAGCTTCGCTCGCAGCCGGTCTGGAGCGAGGCTCTTTCCTCTCTTTTCTGCCATCACAGTACAGTTGGATGT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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