Basic Information
VIS ID
TVIS10000622
Fusion event
HBV-CAAP1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
26851678/26851680 (Hg38)
End
26851678/26851680 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA9C
Target gene
CAAP1
miRNAs that regulate target gene
hsa-mir-103a-3p ; hsa-mir-26b-5p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-101-2/Upstream/5339495; hsa-let-7a-1/Downstream/2011946;
Nearest TSS
ENST00000422679/Upstream/49947; ENST00000518614/Downstream/35798;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1172994, chr9-CpG: 69/Downstream/40610
Upstream sequence
gtacacacatcctaaacaagtttctgagaatgcttctgtctagtttttatgggaagatatttcctttttcaccttaggcctcaatgcgctccaaatgtgc
Downstream sequence
TTAAACAGGGTTCTGGTAGAATAAAAGTTTGATATCAAAAATGAAAATACCCAAAAGGGAAAAATGAAGGCAGAACAGCTGTCTCAATTTCCAAGCATCG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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