Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000625
Fusion event
HBV-GGNBP2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
Start
End
34936003/36579573 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1180/Upstream/4229371; hsa-mir-10226/Downstream/454172;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/33972, chr17-CpG: 95/Downstream/12050
Nearest cancer related gene
GGNBP2(TSG, No orient, 0)
Upstream sequence
TGAATCTTAATGTAAGCCACCAGTGCCTAAAAGGACTGTCCATCACTGATAGAGCTTCATGGATTTGGCTGGATATTGTTACATGGCTTTGGGTTGGAGT
Downstream sequence
GGGGGTGGTCTAGGGAACTGGGATTTAGAAGAAGTTGATGGATTTAAAAAAATGTTTTTAATCCTGTTAACTTTGCTAGCTTTGGTTTTTAGACTTTCTC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.