Basic Information
VIS ID
TVIS10000693
Fusion event
HBV-chr8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
28455384/28597867 (Hg38)
End
28455384/28597867 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/92685; hsa-mir-10400/Downstream/1359405;
Nearest TSS
ENST00000518652/Upstream/34804; ENST00000520940/Downstream/2602;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/102824, chr8-CpG: 118/Downstream/24251
Nearby gene
FZD3(-23599) ; EXTL3(+103606) ;
Nearest cancer related gene
EXTL3(TSG, +103606) ;
Upstream sequence
TAGGAATCATGCCCTGCCTCACTGATTTAGACAGAAGTATCAAGAGTGGAAAGAAAATATGCAAATAATAAAGCATCTCAAGTGTTCCTATTTTGGAGGT
Downstream sequence
gatggagtttcactctgttgcccaggctggagtgcagtgccgcgatctcggctcactgcaacctcaactgcccagattcaagggattcttgtgcctcagc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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