Basic Information
VIS ID
TVIS10000700
Fusion event
HBV-chr2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
216351907/215487184 (Hg38)
End
216351907/215487184 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/1729025; hsa-mir-1244-1/Downstream/2413329;
Nearest TSS
ENST00000437798/Upstream/10517; ENST00000422353/Downstream/45949;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/51047, chr2-CpG: 51/Downstream/525992
Nearby gene
FN1(-51116) ; LINC00607(+124379) ;
Upstream sequence
GAGATGCGGGTAAGTAAGCAGTAGGGACGGGCAGAGCAGTAACTAAGTTGTGTTCATAGGTATTGTGCAAGTTCTTAAGTAGGCTGGAAGCACATGGTTA
Downstream sequence
TGGCAAGTGTGGAGTTATTTCCCCATTTTTAACTCAGCAGGATGACTCCTGTTGTTGACCTAAGAATCACAGGATGAGAGGAAGAAACCTGCCAAGGCAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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