Basic Information
VIS ID
TVIS10000721
Fusion event
HBV-chr5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
157907401/158480393 (Hg38)
End
157907401/158480393 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/3650853; hsa-mir-103a-1/Downstream/1994009;
Nearest TSS
ENST00000502646/Upstream/15928; ENST00000522704/Downstream/4797;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/621147, chr5-CpG: 25/Downstream/570977
Nearby gene
LINC02227(-70620) ; EBF1(+215522) ;
Upstream sequence
tggttttatacgtgtttggtagttcctcctgcattcattcttctccctgctgccttgtgaggaaggtgcctttcttccccttcatgttctgccatgattg
Downstream sequence
GTAATGGAAACTGGAGGCCACCAATTTATTGCACTTCCTCTGGACTTTCTGGGTGGATTTGTTTGGTGGTAAGCATGAGCTTCCTCAGCCTTTCTCACCC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate