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VISDB
Viral Integration Site DataBase
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TVIS10000723
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000723
Fusion event
HBV-TERT integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
1295202/1295087 (Hg38)
End
1295202/1295087 (Hg38)
Location type
Promoter
Target gene
TERT
miRNAs that regulate target gene
hsa-mir-138-5p
;
hsa-mir-498
;
hsa-mir-193b-3p
;
hsa-mir-335-5p
;
hsa-mir-512-5p
;
hsa-mir-1207-5p
;
hsa-mir-1266-5p
;
hsa-mir-1182
;
hsa-mir-181a-5p
;
hsa-mir-6776-3p
;
hsa-mir-197-3p
;
hsa-mir-6740-3p
;
hsa-mir-6760-3p
;
hsa-mir-532-5p
;
hsa-mir-3064-5p
;
hsa-mir-422a
;
hsa-mir-346
;
hsa-mir-1226-3p
;
hsa-mir-1255a
;
hsa-mir-1255b-5p
;
hsa-mir-143-3p
;
hsa-mir-3161
;
hsa-mir-3605-5p
;
hsa-mir-3620-3p
;
hsa-mir-3682-3p
;
hsa-mir-4323
;
hsa-mir-4712-3p
;
hsa-mir-4733-3p
;
hsa-mir-4758-3p
;
hsa-mir-4770
;
hsa-mir-6088
;
hsa-mir-7112-3p
Nearest miRNA
hsa-mir-4635/Upstream/232113; hsa-mir-10397/Downstream/14223;
Nearest TSS
ENST00000502646/Upstream/18;
ENST00000605200/Downstream/26742;
Nearest CpG islands
chr5-CpG: 485/Target
, None/Upstream, None/Downstream
Nearest cancer related gene
TERT
(OG, No orient, 0)
Upstream sequence
TGCCCGGGTCCCCAGTCCCTCCGCCACGTGGGAAGCGCGGTCCTGGGCGTCTGTGCCCGCGAATCCACTGGGAGCCCGGCCTGGCCCCGACAGCGCAGCT
Downstream sequence
aggggaggggctgggagggcccggagggggctgggccggggacccgggaggggtcgggacggggcggggtccgcgcggaggaggcggagctggaaggtga
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Sample Information
×
Sample name
071129T
Sample type
Tumor
Gender
Female
CpG Island Information
×
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