Basic Information
VIS ID
TVIS10000730
Fusion event
HBV-chr11 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
63161833/63394361 (Hg38)
End
63161833/63394361 (Hg38)
Location type
ncRNA_intronic
Target gene
MIR3680-1 ; MIR3680-2
Nearest miRNA
hsa-mir-129-2/Upstream/601590; hsa-let-7a-2/Downstream/947488;
Nearest TSS
ENST00000527297/Upstream/24553; ENST00000394618/Downstream/96171;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/467061, chr11-CpG: 52/Downstream/96545
Upstream sequence
tttataccttggttttttggtttttctttttttttaattctatttttgttttataggtcctgtgagatttaggctttaaagaggttctattttaatgtgt
Downstream sequence
ttccaggatttgtttcaagatttagaggtccttttagcaattcttgtaggggtggcttagtaatggtgaattctctcagcatttgtttatctgaaaaaga
Target sequence
AAGGTCAGGGCAGCAATACCTTCCCATGACTGTCACTTATTTACAAACTCATCCATATCCTTCTAAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate