Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000786
Fusion event
HBV-ZC3H11A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
End
203790410/203821282 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-27b-3p ; hsa-mir-129-5p ; hsa-mir-503-3p ; hsa-mir-1238-5p ; hsa-mir-4460 ; hsa-mir-4481 ; hsa-mir-4536-5p ; hsa-mir-4727-3p ; hsa-mir-4745-5p ; hsa-mir-4758-5p ; hsa-mir-6504-3p ; hsa-mir-185-5p ; hsa-mir-4306 ; hsa-mir-4644 ; hsa-mir-5192 ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-mir-137 ; hsa-mir-3591-5p ; hsa-mir-6857-3p ; hsa-mir-4494 ; hsa-mir-140-5p ; hsa-mir-6718-5p ; hsa-mir-203b-5p ; hsa-mir-4499 ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-4752 ; hsa-mir-6833-5p ; hsa-mir-4753-3p ; hsa-mir-7847-3p ; hsa-mir-6770-5p ; hsa-mir-130b-5p ; hsa-mir-425-5p ; hsa-mir-3154
Nearest miRNA
hsa-mir-101-1/Upstream/1818046; hsa-mir-1182/Downstream/1627020;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/25117, chr1-CpG: 28/Downstream/40097
Upstream sequence
actccctttgctcgcgctctcttgctgccatgtaagacttgtttgtgtcttgcgtcctgttcacctcctgccataattataagtttcctgaagcctcccc
Downstream sequence
agccatgcagaactgtgagttagttaaaccttttttttttaaataaatttcccagtctcagatagttctttatagcaatgtgaaaatggactaatacaTG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.