Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000789
Fusion event
HBV-EPS8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
Start
End
15947636/15794702 (Hg38)
Location type
Promoter
Target gene
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-552-5p ; hsa-mir-589-3p ; hsa-mir-4262 ; hsa-mir-892c-5p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-606 ; hsa-mir-543 ; hsa-mir-1273f ; hsa-mir-129-5p ; hsa-mir-3529-5p ; hsa-mir-379-5p ; hsa-mir-4451 ; hsa-mir-4534 ; hsa-mir-4650-3p ; hsa-mir-6832-5p ; hsa-mir-8082
Nearest miRNA
hsa-mir-1244-3/Upstream/2878784; hsa-let-7i/Downstream/1878597;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/4896, chr12-CpG: 69/Downstream/87295
Nearest cancer related gene
EPS8(OG, No orient, 0)
Upstream sequence
aacaaatataattcgatttatgaggcaaaaaaactaattagctattatctggctgtataaagaaataaaaattaaaatcataaataaatatctaagatga
Downstream sequence
ctaggcatacgtgaaaagaacccactagaacttttggaaaagaaaaatataactgctaaaatataaaaccccataaatgagttaaagagtagattaaaca
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.