Basic Information
VIS ID
TVIS10000799
Fusion event
HBV-chr19 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
41336720/40830815 (Hg38)
End
41336720/40830815 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/460908; hsa-let-7e/Downstream/1038812;
Nearest TSS
ENST00000633603/Upstream/23572; ENST00000594187/Downstream/6395;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/18569, chr19-CpG: 26/Downstream/17731
Nearby gene
RAB4B-EGLN2(-22374) ; CYP2A6(+12723) ;
Upstream sequence
gatagcaatggttgtattcctctgccagaaaccatgccctcctgctgggggctctcttttacccctatacaatcagtctcggtttcggaaactactccct
Downstream sequence
ctcactgcacctttcaacctaaggatgatgatggcgtctccttattgtaagccatagagtgcttcaacgtcttgtagggttctttcacactgccctccac
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate