PDZRN4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000800
Fusion event
HBV-PDZRN4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
GRCh37/hg19
Start
41869446/41475644 (Hg38)
End
41869446/41475644 (Hg38)
Location type
Intronic
Target gene
PDZRN4
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-340-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-4719 ; hsa-mir-3613-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-583 ; hsa-mir-1276 ; hsa-mir-4311 ; hsa-mir-7844-5p ; hsa-mir-4282
Nearest miRNA
hsa-mir-1244-3/Upstream/15601565; hsa-let-7i/Downstream/848056;
Nearest TSS
ENST00000382841/Upstream/2134; ENST00000548316/Downstream/33907;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/286471, chr12-CpG: 16/Downstream/97819
Upstream sequence
ATTGTAGAAAATTCTCATAAGAACATTCACGTACTCAAAGTGACTTTTATTTCTTGATTATAAATAGCAAAGTATTTTGGCCCTGTGTTCTCCTGGATCT
Downstream sequence
AAACCACTCTGAAAGAGCAAGTCAATGGCATAATATTAGCGCTCAAATTTTGTTTATTTCTTTTATACATAATTTCATGAAAACCATAATTCCTTTTGTA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate