Basic Information
VIS ID
TVIS10000805
Fusion event
HBV-LOC105370214 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr13
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
57230579/56656445 (Hg38)
End
57230579/56656445 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA13B
Target gene
LOC105370214
Nearest miRNA
hsa-mir-1297/Upstream/1481897; hsa-mir-1267/Downstream/4543353;
Nearest TSS
ENST00000623511/Upstream/1072921; ENST00000377931/Downstream/484473;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/3454235, chr13-CpG: 25/Downstream/484392
Nearby gene
MIR5007(-1481896) ; PRR20A(+484473) ;
Upstream sequence
GATACTGCTATAAATTTGTTAGAGAAGTCTGAAAAAAATTGTATGTATATTATTTTTTCCAATTAAATACTTCCAGCTTTTATGGGGGGCAAGTCTGTAT
Downstream sequence
TTTATGAAGTATTGTGGATAAATATACCAATACATATCTTCCTACAGACGATATAGAAATAAAGTGATAGAGTTTAGTCaaatttaaattaattaataat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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