Basic Information
VIS ID
TVIS10000814
Fusion event
HBV-GGACT integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr13
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
101243775/100591521 (Hg38)
End
101243775/100591521 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA13D
Target gene
GGACT
miRNAs that regulate target gene
hsa-mir-5191 ; hsa-mir-3907 ; hsa-mir-4790-3p ; hsa-mir-521
Nearest miRNA
hsa-mir-1297/Upstream/948372; hsa-mir-1267/Downstream/1376121;
Nearest TSS
ENST00000623511/Upstream/1993; ENST00000457843/Downstream/45087;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/2549, chr13-CpG: 177/Downstream/82554
Upstream sequence
tgtattagtctgttcttgcattgctataaagagctacctgagacttggtaatttataaagaaaagaggtttgactcacagttccacaggctgtacaggaa
Downstream sequence
gcatggctggggaagcctcaggaaacttacgattatggcagaaggtgaagaggaaagagtcacatcttaaattcttaaacagccagagaaggagaaagag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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