Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000816
Fusion event
HBV-PPIL6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
End
109724222/109403019 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-550b-2-5p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-1227-3p ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-1273a ; hsa-mir-661 ; hsa-mir-4537 ; hsa-mir-4486 ; hsa-mir-5186 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-4797-5p ; hsa-mir-1321 ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-211-3p ; hsa-mir-3612 ; hsa-mir-4252 ; hsa-mir-4270 ; hsa-mir-4327 ; hsa-mir-4441 ; hsa-mir-455-3p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-6754-5p ; hsa-mir-4300 ; hsa-mir-4328 ; hsa-mir-4487 ; hsa-mir-5591-5p ; hsa-mir-6128 ; hsa-mir-6726-5p ; hsa-mir-920
Nearest miRNA
hsa-mir-10398/Upstream/2618799; hsa-mir-1202/Downstream/9666028;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/20129, chr6-CpG: 132/Downstream/37173
Upstream sequence
attgatttctgctgtaacctttattatttattttcttctgcttaatttggatttcattttctcctctttttctggtttcctaaagtagaacttaaatgat
Downstream sequence
CGTCTGCTCACCTCGGTATTTCTCGATCTTTCCAACCCCTCTGCTTTCCTTCTGCCTCTTTACACTTCTTTTCAAGCTTCCATAAAGCTCTAAAATTAAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.