VISDB Viral Integration Site DataBase

VIS ID

TVIS10000842

Fusion event

HBV-HMGA2 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr12

Cytoband

q14.3

Reference genome

Start

End

66241628/65847848 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26a-5p ; hsa-mir-125b-5p ; hsa-mir-34a-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-let-7g-5p ; hsa-let-7c-5p ; hsa-let-7a-5p ; hsa-mir-98-5p ; hsa-mir-370-3p ; hsa-mir-185-5p ; hsa-mir-29b-3p ; hsa-mir-196a-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-204-5p ; hsa-mir-760 ; hsa-let-7f-5p ; hsa-mir-154-5p ; hsa-mir-3199 ; hsa-mir-8052 ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-let-7i-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-196b-5p ; hsa-mir-491-5p ; hsa-mir-92b-3p ; hsa-mir-1296-3p ; hsa-mir-4257 ; hsa-mir-4458 ; hsa-mir-4461 ; hsa-mir-4500 ; hsa-mir-4727-3p ; hsa-mir-6847-5p ; hsa-mir-6857-5p ; hsa-mir-6869-5p ; hsa-mir-33a-5p ; hsa-mir-33b-5p ; hsa-mir-142-3p ; hsa-let-7c-3p ; hsa-mir-508-3p ; hsa-mir-648 ; hsa-mir-2052 ; hsa-mir-3529-3p ; hsa-mir-365a-5p ; hsa-mir-365b-5p ; hsa-mir-145-5p ; hsa-mir-23b-3p ; hsa-mir-493-5p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-4445-5p ; hsa-mir-1244 ; hsa-mir-219a-5p ; hsa-mir-4782-3p ; hsa-mir-6766-3p ; hsa-mir-3143 ; hsa-mir-4450 ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-543 ; hsa-mir-490-3p ; hsa-mir-33b-3p ; hsa-mir-633 ; hsa-mir-495-3p ; hsa-mir-107 ; hsa-mir-485-5p ; hsa-mir-1297 ; hsa-mir-106a-5p ; hsa-mir-10a-3p ; hsa-mir-1245b-3p ; hsa-mir-1252-3p ; hsa-mir-1304-5p ; hsa-mir-16-1-3p ; hsa-mir-17-3p ; hsa-mir-194-5p ; hsa-mir-202-3p ; hsa-mir-222-5p ; hsa-mir-30a-3p ; hsa-mir-30d-3p ; hsa-mir-30e-3p ; hsa-mir-3191-5p ; hsa-mir-326 ; hsa-mir-330-5p ; hsa-mir-335-3p ; hsa-mir-3662 ; hsa-mir-3688-3p ; hsa-mir-3978 ; hsa-mir-4261 ; hsa-mir-4418 ; hsa-mir-4720-3p ; hsa-mir-4738-3p ; hsa-mir-4775 ; hsa-mir-4796-3p ; hsa-mir-4804-3p ; hsa-mir-490-5p ; hsa-mir-5003-3p ; hsa-mir-506-5p ; hsa-mir-509-3-5p ; hsa-mir-509-5p ; hsa-mir-518c-5p ; hsa-mir-548ah-3p ; hsa-mir-548am-3p ; hsa-mir-548ar-3p ; hsa-mir-548o-3p ; hsa-mir-5681b ; hsa-mir-591 ; hsa-mir-627-3p ; hsa-mir-629-3p ; hsa-mir-6502-3p ; hsa-mir-6760-5p ; hsa-mir-6764-3p ; hsa-mir-6824-3p ; hsa-mir-6830-3p ; hsa-mir-6878-5p ; hsa-mir-892c-5p

Nearest miRNA

hsa-let-7i/Upstream/1225243; hsa-mir-1178/Downstream/175772;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/21447, chr12-CpG: 30/Downstream/282836

Nearest cancer related gene

HMGA2(OG, No orient, 0)

Upstream sequence

tgtgtcaagctctcaataGGTCATAATTGTTGATGTTAGTACAGTCTCAGGCCCATAATGGTGCTTACTAAATGTTCGGTGAGTAGGATGACAGTTTTTC

Downstream sequence

TTTAGTGTGTATAAAGGATGGCCTTTGAATTTTTGTTTTCCAGTAATGAATGTGGATTTGAATTACATTCTTTGACTTAAAAAAATCCAAACTAATGATT