Basic Information
VIS ID
TVIS10000849
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
194896702/194927572 (Hg38)
End
194896702/194927572 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA1K
Nearest miRNA
hsa-mir-101-1/Upstream/1790989; hsa-mir-1182/Downstream/1654841;
Nearest TSS
ENST00000473358/Upstream/576629; ENST00000496761/Downstream/1133501;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1805478, chr1-CpG: 24/Downstream/1681006
Nearby gene
CDC73(-1672760) ; KCNT2(+1298208) ;
Nearest cancer related gene
CDC73(TSG, -1672760) ;
Upstream sequence
TATCAAGCTATACTATAAATAATGGTCAATATCAGTGGAGTATGAGTATCAGATATACATATGTCTTGAATATCACAAGGACATATATTTAGCATGACAT
Downstream sequence
TTATTTCCCTTTCTAATTCTCTATATtatgaactggatgtctatcataaactggatgctttctgacccatctagccataaattgggtcatgcacagcagc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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