Basic Information
VIS ID
TVIS10000857
Fusion event
HBV-chr11 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
191897/191897 (Hg38)
End
191897/191897 (Hg38)
Location type
Promoter
Target gene
ODF3 ; SCGB1C1 ; SCGB1C2
Nearest miRNA
hsa-let-7a-2/Downstream/17439;
Nearest TSS
ENST00000527297/Upstream/52285; ENST00000342878/Downstream/1183;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/64120, chr11-CpG: 184/Downstream/15078
Upstream sequence
AAcctaaccctaaccctaacccctaacccctaaccctaaccctaaccctaaccctaacccctaacccctaaccctaaccctaaccctaacccctacccct
Downstream sequence
aacccctaacccttaccggtgaccctactgtatccctgactcctaaccaacgttgatccctaaccctaaaccccttactgtaactataatcttcatccca
Target sequence
tgacaccaagagggatccccttggctaagtctccattgtggtgaaaatgagaataggaggaccccaaaagcccttgacagcaaggacattaacaaccta
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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