Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene265292542588055026171128261708712621738126158091261758242616616426171468261728732617501926198786262004992617710626178448261578222615907226164998261661602619162826191896261717222617187626193421261935722618518226185291261632622616332126204902
Basic Information
VIS ID
TVIS10000861
Fusion event
HBV-chr21 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
27577221/26204902 (Hg38)
End
27577221/26204902 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/630858; hsa-mir-3197/Downstream/749059;
Nearest TSS
ENST00000624081/Upstream/33774; ENST00000452460/Downstream/145732;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/34012, chr21-CpG: 61/Downstream/367789
Nearby gene
APP(-33775) ; CYYR1(+261307) ;
Upstream sequence
tggagtgcagtggcacgatctcggctcactgcaagctctgcctcccagattcacgccattctcctgcctcagcctcccgagtaactgggacggactacag
Downstream sequence
gcgcccaccaccgcgcccgactcattttttttttttttgtattttcagtagagatggcatttcaccatgttagccaggatgatctcgatctcctgacttt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate