Basic Information
VIS ID
TVIS10000862
Fusion event
HBV-chr16 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
32250419/32239098 (Hg38)
End
32250419/32239098 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/1345113; hsa-mir-11401/Downstream/1924480;
Nearest TSS
ENST00000527434/Upstream/50765; ENST00000563025/Downstream/13621;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/36137, chr16-CpG: 17/Downstream/2150
Nearby gene
HERC2P4(-50985) ; TP53TG3D(+14231) ;
Upstream sequence
CCAGCACGGGGAGGAAAGTAGCTCTAAGGGGGACACATTCCCACTTCTTTCCCTTCTAGCAAGTTTGAAAGCTAATTGTAAATGCAGGTGGATATGTAGA
Downstream sequence
AAATGAGGGCATGCTATAACATCTCATCACATGAGGTTGTGACCAGGAGTTTTTAATCCTAGCTCTGAGAGCTGCAAATGGGAATTGGAAGTTTTTCCAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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