AHRR _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000913
Fusion event
HBV-AHRR integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
428156/428041 (Hg38)
End
428156/428041 (Hg38)
Location type
Intronic
Target gene
AHRR
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26a-5p ; hsa-mir-18a-5p ; hsa-mir-125b-5p
Nearest miRNA
hsa-mir-10397/Downstream/634855;
Nearest TSS
ENST00000502646/Upstream/123; ENST00000507048/Downstream/3984;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/6405, chr5-CpG: 76/Downstream/14664
Nearest cancer related gene
AHRR(TSG, No orient, 0)
Upstream sequence
taaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaac
Downstream sequence
CTGCTGGCGGCCCCCACAAAACACCTCCACACTCAGTGTTTTCTGTGTCTTCTTTCTTCATTTCCAGCCAGTAATAAGTCAGTTTCGTGTCGTAAAAGTC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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