NELL1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000933
Fusion event
HBV-NELL1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
21563428/21541882 (Hg38)
End
21563428/21541882 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA11C ; FRA11I
Target gene
NELL1
Nearest miRNA
hsa-mir-210/Upstream/1781799; hsa-let-7a-2/Downstream/1877223;
Nearest TSS
ENST00000527297/Upstream/258145; ENST00000530837/Downstream/571566;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/871583, chr11-CpG: 88/Downstream/650744
Upstream sequence
CTTTTTCTAATATGTGTTTTTATATGCAAATTTCCTGACAAGTATTATATGATAGTCAACatttaacctcccttcacctcagttccctcacctgtcacat
Downstream sequence
gaaaacaataacagtaATACtaataagagataacatttattgagagttttactttgtgccagacactgctctcagcaatttacaaaagcatcaacctcat
Target sequence
TTTTATCAcaagtagtttatttgggacaaggtgaccccaggaaagggctgtagaggagtagggaaatgaaacacagaagagaatgaagccatggcagagttcattaattatcaagtg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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