Basic Information
VIS ID
TVIS10000934
Fusion event
HBV-chr6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
GRCh37/hg19
Start
66446619/65736726 (Hg38)
End
66446619/65736726 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/8346514; hsa-mir-10524/Downstream/5640234;
Nearest TSS
ENST00000381078/Upstream/29501; ENST00000449928/Downstream/2152613;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/435138, chr6-CpG: 34/Downstream/51056
Nearby gene
EYS(-29501) ; SLC25A51P1(+51153) ;
Upstream sequence
ACTAACTCTAAAAGGTGAGCCTGGCTAGAATTAATATAATTTCATTGAGAGAAGCTTGTATCAAATTATTGACATAAATAGCAGATAGAGGTTACAAAGT
Downstream sequence
tcctagagccatctgtaatctcattccatttttattttatttaaatatccgaacgatggcaaaccctattttctgcttagtccatgacagaacttcttta
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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