Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000962
Fusion event
HBV-GRM5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q14.3
Reference genome
Start
End
88711682/88978514 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-510-3p ; hsa-mir-6815-3p ; hsa-mir-513b-5p ; hsa-mir-4719 ; hsa-mir-892b ; hsa-mir-582-3p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548n
Nearest miRNA
hsa-mir-10392/Upstream/801921; hsa-let-7a-2/Downstream/1577260;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/469120, chr11-CpG: 40/Downstream/87267
Upstream sequence
agaagaattgtcttggaccacacatcaaatacagtaacattaacaacagcagatgagcttaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
Downstream sequence
aacctcataatgtcttaagaaagtttatgaatttgtgttggggagcatttaaagccatcctgggctgcagtcgcatgtggcttacaaggataagggttgg
Target sequence
AGAATATTCCACAAAGAGAAAAATTATCATTAAAAACTTTGAACATCAggctgggtatgatgactcacgcctgtaatcccagcactctgggaggct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.