Basic Information
VIS ID
TVIS10000964
Fusion event
HBV-chr11 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q25
Reference genome
GRCh37/hg19
Start
134946519/134946519 (Hg38)
End
134946519/134946519 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7a-2/Upstream/1047938;
Nearest TSS
ENST00000527297/Upstream/210923; ENST00000528497/Downstream/4189;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/183426, chr11-CpG: 78/Downstream/14916
Nearby gene
LOC283177(-570964) ;
Upstream sequence
tcctctttgcagccctgaataatcagggtcagagatcagttagggttagggttagggttagggttagggttagggttagggttagggttagggttagNNN
Downstream sequence
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Target sequence
aaaagtattacttgaacccaggagttcaagactagcatgggcaacactgagactccagctctacaaaaaatttaaaaattagctaagcatggtggcat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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