GPHN _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000973
Fusion event
HBV-GPHN integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
67494515/67027798 (Hg38)
End
67494515/67027798 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
GPHN
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-375
Nearest miRNA
hsa-mir-208a/Upstream/1556612; hsa-mir-1185-1/Downstream/414057;
Nearest TSS
ENST00000550708/Upstream/57982; ENST00000556501/Downstream/30851;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/518281, chr14-CpG: 95/Downstream/213238
Upstream sequence
AACTTTTCTAGATTTTTTTAGTATATTTTAATGGAATTCAGAAtttttattgatatataatatttgtacatatttatggagtacaggtgatatcttgata
Downstream sequence
catgcatagaatttgtaatgatcaagtcagggtatttgggatatccatcacctcttgagcatttatcatttcttcatgttgggaacatttcaaatcctat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate