MGAT4A _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000992
Fusion event
HBV-MGAT4A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
99327807/98711344 (Hg38)
End
99327807/98711344 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2A
Target gene
MGAT4A
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-409-3p ; hsa-mir-376a-5p ; hsa-mir-4423-3p ; hsa-mir-376a-2-5p ; hsa-mir-3132 ; hsa-mir-197-5p ; hsa-mir-564 ; hsa-mir-3622a-5p ; hsa-mir-5582-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/1912991; hsa-mir-10b/Downstream/2598106;
Nearest TSS
ENST00000437798/Upstream/47871; ENST00000496794/Downstream/15352;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/102485, chr2-CpG: 150/Downstream/19075
Upstream sequence
ACTAACAAGTTAATTTGGAAAAAAAAAAAAAAAAAAGGACCCAGACAACAAGTAACCTAGATTTAAATTACATCGGGGGAAGCAACCAGGTTCCTGGCCC
Downstream sequence
CTACTCAATGCTCAGTCAATAATCCTGATCACATTTGACACGAATGGTCCCAGAAGACACTCACTTTTTTATTTTCCAGCTTGATGAGATTTCTAAAATC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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