GSK3B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10000994
Fusion event
HBV-GSK3B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
q13.33
Reference genome
End
119561134/119842287 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7g/Upstream/2991920; hsa-mir-12124/Downstream/242277;
Nearest cancer related gene
GSK3B(TSG, No orient, 0)
Upstream sequence
GCATCTAGAAGGTGAGTTGGGGCTAAAGATTGGATTGAAGATCAAAAGAGAAGAGGAAAAGGATCAAAGGGGACGAAAAGAAGAGAAGGAGAAGGAGGTC
Downstream sequence
CAGCACACCCTAGCTCTAACCCGTGAATAATTTTTTTTTGGTATATAAGAGTCTTGTCACATTCTGATCTAAATCTCAGTTAAACATATTTGCATTGCAG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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